AMR Exchange: Antifungal Resistance: Understanding this Growing Global Threat

 

'No common symptoms' for deadly fungal disease sweeping US poses 'challenges' for experts

Story by Fionnuala Boyle

CDC says cases of lethal fungus tripled in recent years

Candida auris was reported in the US in 2016

The synanamorphs and teleomorphs of Phoma have been poorly investigated thus far, except for the P. lingam complex. Few synanamorph relationships have thus far been confirmed by means of molecular techniques. Arenal et al. (2000, 2004) demonstrated P. epicoccina and Epicoccum nigrum to be synanamorphs by employing ITS sequence data, and synonymised these species after further microscopical studies." 

Biology and recent developments in the systematics of Phoma, a complex genus of major quarantine significance.

M. Aveskamp, J. Gruyter, P. Crous

The other black fungi: exploring the opportunists in the order Pleosporales

Sarah Ahmed - Ervin M Alcanzo - Qirui Li - Nadir Musa Abuzeid -Xin Zhou - Peiying Feng -

Dea Garcia-Hermoso - Sybren de Hoog

"Additionally, deep-seated infections generally exhibit a predilection for immunocompromised hosts, but cases with cerebral dissemination are more common in immunocompetent individuals. "

Coelomycetous fungi in human disease. A review: Clinical entities, pathogenesis, identification and therapy 

Deanna A. Sutton

Coelomycetous Fungi in the Clinical Setting: Morphological Convergence and Cryptic Diversity

Nicomedes Valenzuela-Lopez, Deanna A. Sutton, José F. Cano-Lira, Katihuska Paredes, 

Nathan Wiederhold, Josep Guarro, and Alberto M. Stchigel

David W. Warnock, Editor

David W. Warnock, University of Manchester;

The phoma-like dilemma

, ,   

Rungtiwa Phookamsak, Jian-Kui Liu, Eric H. C. McKenzie, Dimuthu S. Manamgoda, Hiran Ariyawansa, Kasun M. Thambugala, Dong-Qin Dai, Erio Camporesi, Ekachai Chukeatirote, Nalin N. Wijayawardene, Ali H. Bahkali, Peter E. Mortimer, Jian-Chu Xu & Kevin D. Hyde 

 

Resolving the Phoma enigma

"Results of a phylogenetic study including the type species of all nine Phoma sections and allied coelomycetous genera demonstrated that all nine sections grouped in the Pleosporales ." 

Q. Chen,  J.R. Jiang, G.Z. Zhang, L. Cai, and P.W. Crous

Pleosporales       

Ying Zhang,  Pedro W. Crous,  Conrad L. Schoch  and Kevin D. Hyde

A new pleosporalean fungus isolated from superficial to deep human clinical specimens.

Nicomedes Valenzuela-Lopez, M Teresa Martin-Gomez, Ibai Los-Arcos, Alberto M Stchigel, Josep Guarro, José F Cano-Lira   

  

Draft Genome Sequence of Dematiaceous Coelomycete Pyrenochaeta sp. Strain UM 256, Isolated from Skin Scraping

Authors: Su Mei Yew, Chai Ling Chan, Tuck Soon Soo-Hoo, Shiang Ling Na, Seong Siang Ong, Hamimah Hassan, Yun Fong Ngeow, Chee Choong Hoh, Kok Wei Lee, Wai Yan Yee, Kee Peng Ng   

Antimicrobial blue light inactivation of international clones of multidrug-resistant Escherichia coli ST10, ST131 and ST648

International clones of multidrug-resistant Escherichia coli have been a leading cause of human and animal infections worldwide. Microbial inactivation by blue light has been proposed as an effective treatment for superficial infections and surface contamination.

Carolina dos Anjos, Caetano P. Sabino, Vanessa Bueris, Miriam R. Fernandes, Fabio C.Pogliani, Nilton Lincopan, 

Fábio P. Sellera

Antimicrobial Blue Light And Quinine Combo Effective For Treatment Of Mold Infection: Study

New Insights into the Bacterial Targets of Antimicrobial Blue Light

Escherichia coli ST131, an Intriguing Clonal Group

In 2008, a previously unknown Escherichia coli clonal group, sequence type 131 (ST131), was identified on three continents. Today, ST131 is the predominant E. coli lineage among extra-intestinal pathogenic E. coli (ExPEC) isolates worldwide.

Retrospective studies have suggested that it may originally have risen to prominence as early as 2003

Marie-Hélène Nicolas-Chanoine, Xavier Bertrand, and Jean-Yves Madec

Global dissemination of a multidrug-resistant Escherichia coli clone

Nicola K. Pettya,b,c,1, Nouri L. Ben Zakoura,b,1, Mitchell Stanton-Cooka,b, Elizabeth Skippingtona,b, Makrina Totsikaa,b,Brian M. Fordea,b, Minh-Duy Phana,b, Danilo Gomes Moriela,b, Kate M. Petersa,b, Mark Daviesa,b,d, Benjamin A. Rogerse,Gordon Dougand, Jesús Rodriguez-Bañof,g, Alvaro Pascualf,g, Johann D. D. Pitouth,i, Mathew Uptonj,David L. Patersona,e, Timothy R. Walshk, Mark A. Schembria,b,2, and Scott A. Beatsona,b,

Light as a potential treatment for pandemic coronavirus infections: A perspective 

"The evidence shows that violet/blue (400–470 nm) light is antimicrobial against numerous bacteria, and that it accounts for Niels Ryberg Finsen's Nobel-winning treatment of tuberculosis. Further evidence shows that blue light inactivates several viruses, including the common flu coronavirus, and that in experimental animals, red and near infrared light reduce respiratory disorders, similar to those complications associated with coronavirus infection."

Chukuka Samuel Enwemeka, Violet Vakunseh Bumah, Daniela Santos Masson-Meyers 

Proceedings of Light-Activated Tissue Regeneration and Therapy Conference

First book to present the mechanism explaining why light is effective in the treatment of so many illnesses and diseases.

• Offers a systematic approach to the field of Light-Activated Tissue Regeneration and Therapy covering theory, basic research, clinical studies, and therapies.

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• Includes extensive papers and coverage on such interesting topics as pain, wound healing, diabetes, cardiovascular and stroke repair, neuroscience/progenitor, and stem cells.

Editors: Ronald Waynant, Darrell B. Tata

                           

 

SUPER-SUPERBUG CLONES INVADE THE GULF STATES   

UQ Centre for Clinical Research group leader Dr Hosam Zowawi said his team had witnessed rapid growth of the new multi-drug resistant clones – variants of existing superbugs in the Gulf States, but which had never before seen in the region.

                                   

Unusual forms of ‘nightmare’ antibiotic-resistant bacteria detected in 27 states

The CDC has warned of the antibiotic-resistant bacteria for years, but these “nightmare bacteria” are “virtually untreatable” and capable of spreading genes that make them “impervious” to most antibiotics, Scientific American reported

Sleepwalking towards an antibiotic apocalypse

“Preparedness 101: Zombie Apocalypse” was a blog post written by the United States Centers for Disease Control and Prevention warning Americans to prepare for natural disasters ­– particularly pandemics – as though they were being hunted by flesh-eating zombies.